An Injectable Self-Assembling Collagen-Gold Hybrid Hydrogel for Combinatorial Antitumor Photothermal/Photodynamic
Ruirui Xing1,2, Kai Liu3,4,5, Tifeng Jiao1,2
1State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao, 066004, P. R. China.
Advanced Materials (Deerfield Beach, Fla.)
|March 19, 2016
Abstract:
An injectable and self-healing collagen-gold hybrid hydrogel is spontaneously formed by electrostatic self-assembly and subsequent biomineralization. It is demonstrated that such collagen-based hydrogels may be used as an injectable material for local delivery of therapeutic agents, showing enhanced antitumor efficacy.
Keywords:
antitumor therapycollagen hydrogelselectrostatic self-assemblyin situ sustained releaseinjectable and self-healing properties
