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Published on: December 6, 2016
Obstructive sleep apnea in children with cerebral palsy and epilepsy
John Garcia1, Beverly Wical1, William Wical1
1Gillette Children's Specialty Healthcare, Saint Paul, MN, USA.
Insights
Children with cerebral palsy (CP) and epilepsy face a higher risk of obstructive sleep apnea (OSA). Routine screening using questionnaires is recommended, especially for those with severe CP or co-occurring epilepsy.
Area of Science:
- Pediatric Neurology
- Sleep Medicine
- Developmental Pediatrics
Background:
- Obstructive sleep apnea (OSA) is a significant concern in pediatric populations.
- Cerebral palsy (CP) and epilepsy are common neurological conditions in children that may influence sleep health.
Purpose of the Study:
- To investigate the prevalence and risk factors of OSA in children with CP and/or epilepsy.
- To compare OSA risk across different subgroups of children with CP and epilepsy.
Main Methods:
- A cross-sectional study involving 215 children.
- Utilized the Pediatric Sleep Questionnaire (PSQ), Gross Motor Function Classification System (GMFCS), and chart reviews.
- Grouped participants into those with epilepsy, CP, both, or neither (developmental disability comparison group).
Main Results:
- Children with CP (58%) and CP with epilepsy (67%) showed significantly higher PSQ scores (indicating OSA risk) compared to the comparison group (27%).
- Increased OSA risk correlated with greater CP severity (GMFCS) and the presence of comorbid epilepsy.
- The PSQ identified significantly more children at risk for OSA (46%) than medical record review (8.2%).
Conclusions:
- Children with CP, particularly those with severe forms or co-existing epilepsy, are at an elevated risk for OSA.
- Routine, questionnaire-based screening for OSA should be integrated into the care of children with CP.
Aim:
To examine the risk of obstructive sleep apnea (OSA) in children with cerebral palsy (CP) and/or epilepsy.
Method:
This cross-sectional study employs the Pediatric Sleep Questionnaire (PSQ), the Gross Motor Function Classification System (GMFCS), and chart review to identify symptoms of OSA in children presenting to a multi-specialty pediatric healthcare institution.
Results:
Two-hundred and fifteen patients were grouped into those with epilepsy (n=54), CP (n=18), both (n=55), and neither (comparison group, n=88). The comparison group comprised children with developmental disabilities but not children with typical development. Significantly increased PSQ scores (indicating increased risk of OSA) were found among children with CP (58%) and CP with epilepsy (67%) than among the comparison group (27%; p<0.001 and p<0.0001 respectively). Children with both CP and epilepsy had a greater number of increased PSQ scores compared with CP alone (p<0.05). Increased PSQ scores were observed with increasing CP severity as measured using the GMFCS. The PSQ identified more children at risk of OSA (46%) than did the medical record review for symptoms of OSA (8.2%, p<0.001).
Interpretation:
Children with CP of greater severity or comorbid epilepsy are at increased risk of OSA. This study supports the routine questionnaire-based assessment for OSA as a regular part of the care of all children with CP, especially in those with more severe CP and those with epilepsy.
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