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Klebsiella pneumoniae Liver Abscess: An Emerging Disease

Tasaduq Fazili1, Calden Sharngoe2, Timothy Endy2

  • 1Division of Infectious Diseases, Upstate Medical University, Syracuse, New York.

The American Journal of the Medical Sciences
|March 20, 2016
PubMed

Insights

Klebsiella pneumoniae liver abscesses, once mainly seen in Asia, are now increasingly recognized in the United States. This syndrome often affects middle-aged diabetic men and can lead to metastatic complications like endophthalmitis.

Area of Science:

  • Infectious Diseases
  • Hepatology
  • Microbiology

Background:

  • Klebsiella pneumoniae liver abscess (KPLA) is a serious infection.
  • Historically, KPLA cases were predominantly reported in Asian countries, particularly Taiwan.

Observation:

  • Early reports indicated a predilection for middle-aged diabetic men.
  • Metastatic complications, such as endophthalmitis, were frequently observed.

Findings:

  • The incidence of KPLA is increasing and being recognized more frequently in the United States.
  • The review covers reported cases and explores the pathophysiology of KPLA.

Implications:

  • Increased awareness of KPLA in the US is crucial for timely diagnosis and treatment.
  • Understanding the pathophysiology may lead to improved management strategies for this emerging infectious disease.
Keywords:
Emerging diseaseHyperviscous phenotypeKlebsiella pneumoniaeLiver abscessUnited States

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