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[A comparative study between propofol and etomidate in patients under general anesthesia].
Supriya Aggarwal1, Vipin Kumar Goyal1, Shashi Kala Chaturvedi1
1Departamento de Anestesiologia e Tratamento Intensivo, Faculdade de Medicina e Hospital Mahatma Gandhi, Jaipur, Rajasthan, Índia.
Etomidate offers superior hemodynamic stability and reduced injection pain compared to propofol for anesthesia induction. This makes etomidate a safer choice for patients undergoing general anesthesia.
Area of Science:
- Anesthesiology
- Pharmacology
Context:
- Anesthesia induction is critical, with risks of hypotension and cardiovascular collapse in unstable patients.
- Safe induction agents with minimal adverse effects are needed.
Purpose:
- Compare the hemodynamic effects and adverse events of propofol versus etomidate as induction agents.
- Evaluate patient safety and tolerance during general anesthesia induction.
Summary:
- A prospective randomized study compared propofol (2mg/kg) and etomidate (0.3mg/kg) in 100 ASA I/II patients.
- Etomidate group showed minimal changes in mean arterial pressure and heart rate post-induction compared to propofol.
- Propofol caused more injection pain, while etomidate was associated with higher myoclonus rates.
Impact:
- Etomidate demonstrates better hemodynamic stability during anesthesia induction.
- Etomidate is associated with less pain on injection compared to propofol.
- Findings guide the selection of safer induction agents in anesthesia practice.
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