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Controlled uptake and release of imatinib from ultrasound nanoparticles Cu3(BTC)2 metal-organic framework in
Amir Reza Abbasi1, Maryam Rizvandi1, Azadeh Azadbakht2
1Faculty of Chemistry, Razi University, 67194 Kermanshah, Islamic Republic of Iran.
Abstract:
The porosity of metal-organic frameworks (MOFs) is an important point concerning the possible use of such functional materials for different purposes. In this work, we study uptake and release properties of imatinib (IM) from nano Cu(II)-MOF in comparison with bulk Cu(II)-MOF. To explore the absorption ability of the Cu(II)-MOF to IM, fresh sample of Cu3(BTC)2 was immersed in an aqueous solution of IM and were monitored in real time with UV/vis spectroscopy. Results show that the adsorbed quantity of IM over nano Cu3(BTC)2 (I) is much higher than those over a bulk Cu3(BTC)2 (II).
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