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Unrealistic Optimism Bias01:30

Unrealistic Optimism Bias

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Unrealistic optimism bias is the tendency to overestimate the likelihood of positive outcomes. This cognitive bias makes individuals believe they are less likely to experience failures, setbacks, or risks and more likely to succeed than others. For example, people may assume they are less prone to health issues, accidents, or financial struggles than their peers, even when they share similar risk factors.One key component of this bias is the above-average effect, where individuals perceive...
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Self-Discrepancy Theory02:45

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One influential perspective on what motivates people's behavior is detailed in Tory Higgin's self-discrepancy theory (Higgins, 1987). He proposed that people hold disagreeing internal representations of themselves that lead to different emotional states.  
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Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
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Hindsight Biases01:12

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Hindsight bias leads you to believe that the event you just experienced was predictable, even though it really wasn’t. In other words, you knew all along that things would turn out the way they did. Can you relate this to the phrase "Hindsight is 20/20" now? 
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Self-Discrepancy and Its Effects01:29

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Self-discrepancy theory explains how people compare their actual self to their ideal and ought selves and how mismatches between these self-guides can lead to emotional distress. Developed by E. Tory Higgins, the theory distinguishes among three components of self-concept: the actual self, the ideal self, and the ought self. These refer respectively to how individuals perceive themselves, how they aspire to be, and how they believe they are obligated to be. Emotional well-being, self-esteem,...
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Stereotype Threat and Self-fulfilling Prophecies02:09

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When we hold a stereotype about a person, we have expectations that he or she will fulfill that stereotype. A self-fulfilling prophecy is an expectation held by a person that alters his or her behavior in a way that tends to make it true. When we hold stereotypes about a person, we tend to treat the person according to our expectations. This treatment can influence the person to act according to our stereotypic expectations, thus confirming our stereotypic beliefs. Research by Rosenthal and...
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Related Experiment Video

Updated: Mar 24, 2026

Taking the Next Step: a Neural Coaptation Orthotopic Hind Limb Transplant Model to Maximize Functional Recovery in Rat
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Our aspirations still disappoint.

Samuel M Butman1

  • 1Valley Medical Center, Cottonwood, AZ.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|March 21, 2016
PubMed
Summary
This summary is machine-generated.

Routine thrombectomy in ST-elevation myocardial infarction (STEMI) interventions is not recommended. While it may lower early MACE events, it increases stroke risk during follow-up, making it an unproven adjunct to primary stenting.

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Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Thrombosis Research

Background:

  • Primary percutaneous coronary intervention (PCI) is the standard treatment for ST-elevation myocardial infarction (STEMI).
  • Mechanical thrombectomy aims to remove thrombus during primary PCI, potentially improving outcomes.
  • The efficacy and safety of routine thrombectomy in STEMI remain debated.

Discussion:

  • Two large prospective randomized trials have failed to demonstrate a benefit for routine thrombectomy in STEMI.
  • While thrombectomy might reduce early Major Adverse Cardiovascular Events (MACE), a higher risk of stroke is observed during follow-up.
  • Case-specific clot removal is an unproven adjunct to primary stenting in STEMI therapy.

Key Insights:

  • Routine thrombectomy is not supported by current evidence for STEMI patients undergoing primary PCI.
  • The potential benefit of reduced early MACE is outweighed by an increased risk of stroke in the long term.
  • Current guidelines do not recommend routine use of thrombectomy devices in this setting.

Outlook:

  • Further research may explore specific patient subgroups who could benefit from adjunctive thrombectomy.
  • Focus remains on optimizing primary PCI and medical therapy for STEMI.
  • The development of safer and more effective thrombectomy devices could be a future direction.