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Corneal Donor Tissue Preparation for Descemet's Membrane Endothelial Keratoplasty
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Iris alterations after DSAEK.

A Del Hierro Zarzuelo1, A Boto de Los Bueis1

  • 1Servicio de Oftalmología, Departamento de Córnea, Hospital Universitario La Paz, Madrid, España.

Archivos De La Sociedad Espanola De Oftalmologia
|March 22, 2016
PubMed
Summary

Iris changes can occur after Descemet stripping automated endothelial keratoplasty (DSAEK). This study found that 37.5% of patients developed iris abnormalities, including synechiae and pupil ovalization, post-DSAEK surgery.

Keywords:
Atrofia de irisCorectopiaDescemet's stripping automated endothelial keratoplastyIridocorneal synechiaeIris atrophyQueratoplastia endotelial automatizada con stripping de la DescemetSinequias iridocornealesSíndrome de Urrets ZavalíaUrrets-Zavalía syndrome

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Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Ocular Surface Disease

Background:

  • Descemet stripping automated endothelial keratoplasty (DSAEK) is a common procedure for endothelial dysfunction.
  • Iris complications following DSAEK are not well-documented.

Purpose of the Study:

  • To evaluate the incidence and types of iris changes after DSAEK.
  • To identify potential risk factors associated with these changes.

Main Methods:

  • Retrospective study of 32 DSAEK procedures.
  • Analysis of iris abnormalities including pupil ovalization, atrophy, synechiae, mydriatic pupil, and pigmentary changes.
  • Evaluation of associated factors and surgical outcomes.

Main Results:

  • Iris abnormalities were observed in 12 eyes (37.5%) after DSAEK.
  • Common findings included iris-corneal synechiae (7 eyes), corectopias (9 eyes), and iris atrophy (3 cases).
  • Long-term pigment dispersion was noted in 12 eyes, typically occurring after three months.

Conclusions:

  • Iris changes are a potential complication of DSAEK.
  • Increased intraocular pressure from anterior chamber air may contribute to iris ischemia and secondary alterations.
  • Further investigation into the mechanisms and management of post-DSAEK iris complications is warranted.