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Burden of community-onset bloodstream infections, Western Interior, British Columbia, Canada

K B Laupland1, K Pasquill2, E C Parfitt1

  • 1Department of Medicine,Royal Inland Hospital,Kamloops,British Columbia,Canada.

Epidemiology and Infection
|March 22, 2016
PubMed

Insights

Community-onset bloodstream infections (BSI) significantly impact health, with healthcare-associated BSIs posing a higher mortality risk. Understanding BSI epidemiology is crucial for public health strategies.

Area of Science:

  • Infectious Diseases
  • Epidemiology
  • Public Health

Background:

  • Community-onset bloodstream infection (BSI) is a significant cause of illness and death.
  • Limited epidemiological data exists for non-selected populations.
  • Defining the burden of BSI is essential for healthcare planning.

Purpose of the Study:

  • To determine the incidence and burden of community-onset bloodstream infections (BSI) in a defined Canadian population.
  • To differentiate between healthcare-associated (HA-BSI) and community-associated (CA-BSI) episodes.
  • To analyze risk factors and outcomes associated with community-onset BSI.

Main Methods:

  • Population-based surveillance was conducted in the Interior Health West region of British Columbia, Canada.
  • 1088 episodes of community-onset BSI were identified over the study period.
  • Incidence, hospitalization rates, length of stay, and in-hospital mortality were analyzed.

Main Results:

  • The overall annual incidence of community-onset BSI was 117.8 per 100,000 population.
  • Healthcare-associated BSIs accounted for 58.7% of episodes, with a higher mortality rate (12.7%) compared to community-associated BSIs (7.6%).
  • Elderly males were identified as the highest-risk group, and BSIs led to substantial hospitalization days and mortality.

Conclusions:

  • Community-onset BSI, particularly HA-BSI, represents a significant public health burden.
  • Targeted interventions for high-risk populations and healthcare settings are warranted.
  • Further research into BSI prevention and management is essential.

Keywords:
Bacterial infectionsbloodstream infectionsepidemiology

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