Management of unexplained infertility

Unexplained or idiopathic infertility means no cause can be found to account for the infertility. This depends on the enthusiasm to look for the subtle causes like luteal phase defect (LPD), luteinizing unruptured follicle syndrome (LUFS), abnormal prolactin secretion, psychogenic, environmental, nutritional and immunological factors. Sometimes, these subclinical conditions can be corrected. Failing to identify these treatable conditions, various empirical treatments, laboratory manipulation or assisted reproductive techniques (ART) can be attempted to achieve conception.