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Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
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Somatosensation01:33

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The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
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Related Experiment Video

Updated: Mar 24, 2026

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke
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Sensorimotor dysfunction after limb fracture - An exploratory study.

J Hall1, A Llewellyn2,3, S Palmer3

  • 1Royal United Hospital Foundation Trust, Bath, UK. jane.hall23@nhs.net.

European Journal of Pain (London, England)
|March 22, 2016
PubMed
Summary
This summary is machine-generated.

Recent limb fractures cause immediate sensory and motor deficits, including pain and body perception disturbances. Many patients experience delayed recovery and ongoing pain six months post-fracture.

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Area of Science:

  • Orthopedics
  • Pain Medicine
  • Neuroscience

Background:

  • Chronic pain is linked to sensorimotor dysfunction.
  • Early sensory and motor changes after limb fracture are poorly understood.
  • This study investigates immediate post-fracture effects on sensory and motor function.

Purpose of the Study:

  • To assess sensory and motor performance changes in patients with recent wrist and ankle fractures.
  • To determine the incidence and clinical features of Complex Regional Pain Syndrome (CRPS) post-fracture.
  • To explore body perception disturbances and pain in the fractured limb.

Main Methods:

  • Quantitative Sensory Testing (QST), Motor Imagery (MI), and Body Perception Disturbance (BPD) assessments were performed within 5 weeks post-fracture.
  • CRPS evaluation and recovery assessments were conducted 5 weeks later.
  • Patient-reported outcomes on pain, distress, and function were collected at multiple time points.

Main Results:

  • Fractured limbs showed increased sensitivity to cold and pressure pain (hyperalgesia).
  • Patients reported significantly more difficulty with imagined movements of the fractured limb.
  • Body perception disturbance was evident in the fractured limb, and CRPS signs/symptoms were common (70%).

Conclusions:

  • Limb fracture leads to immediate changes in pain perception, motor planning, and body awareness.
  • Complex Regional Pain Syndrome (CRPS) incidence was 9.4%, with many patients reporting CRPS symptoms.
  • Delayed recovery and persistent pain are common, with only 33% reporting full recovery at 6 months.