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Related Experiment Videos

Prenatal diagnosis using sonographic guided cordocentesis.

E Shalev1, U Dan, E Weiner

  • 1Department of Obstetrics and Gynecology, Central Emek Hospital, Afula, Israel.

Journal of Perinatal Medicine
|January 1, 1989
PubMed
Summary
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Cordocentesis, a prenatal diagnostic tool, successfully diagnosed fetal conditions in 98.5% of cases with minimal complications. This rapid method aids in timely interventions for fetal health.

Area of Science:

  • Perinatology
  • Prenatal Diagnostics
  • Fetal Medicine

Background:

  • Cordocentesis is a valuable diagnostic procedure for prenatal assessment.
  • It aids in identifying intrauterine infections, hematological disorders, and fetal metabolic status.
  • Rapid cytogenetic analysis is a key application.

Purpose of the Study:

  • To present the performance and outcomes of 198 cordocentesis procedures over three years.
  • To evaluate the safety and efficacy of cordocentesis for prenatal diagnosis.
  • To highlight the role of cordocentesis in modern perinatology.

Main Methods:

  • Procedures performed using a 21-gauge spinal needle under real-time ultrasonic guidance.
  • Needle insertion targeted the umbilical cord insertion into the placenta.

Related Experiment Videos

  • Fetal lymphocytes were utilized for chromosomal analysis.

    • Main Results:

    • Successful cordocentesis achieved in 98.5% of cases.
    • Pregnancy termination directly related to the procedure occurred in only 1% of cases.
    • One case of hematoma was observed without fetal damage.

    Conclusions:

    • Cordocentesis is a safe and effective method for prenatal diagnosis, particularly for rapid karyotyping.
    • The technique offers significant advantages in managing pregnancies with suspected chromosomal abnormalities or metabolic issues.
    • Cordocentesis plays a crucial role in early fetal diagnosis and potential treatment.