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Related Experiment Video

Updated: Mar 23, 2026

A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria

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Published on: June 27, 2022

Outcome after hydrogen sulphide intoxication.

Eline A Q Mooyaart¹, Egbert L G Gelderman¹, Maarten W Nijsten²

¹Department of Anesthesiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

|March 22, 2016

Summary

This summary is machine-generated.

Hydrogen sulphide (H2S) intoxication can be fatal, but this study found that some patients survived severe exposures, suggesting a potential protective effect against hypoxia. This may be due to H2S inducing a suspended animation-like state.

Keywords:

Gasotransmitter Hibernation Hydrogen sulfide intoxication Hydrogen sulphide Hypometabolism Out-of-hospital cardiac arrest

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Published on: December 10, 2015

Area of Science:

Toxicology
Environmental Health
Emergency Medicine

Background:

Hydrogen sulphide (H2S) intoxication often results in fatalities.
Animal studies suggest H2S may protect against hypoxia.
Human protective effects of H2S remain largely undocumented.

Purpose of the Study:

To describe the frequency and outcomes of H2S intoxication in a human cohort.
To investigate potential protective mechanisms of H2S in human exposures.

Main Methods:

Retrospective analysis of 35 H2S intoxication accidents (56 victims) from 1980-2013.
Examined survival rates and outcomes in relation to exposure and resuscitation.

Main Results:

At least 43% (24/56) of victims survived.
Survival rate was 75% (6/8) for patients receiving on-scene cardiopulmonary resuscitation.
Favorable outcomes were observed even after prolonged exposure (>45 min) to high H2S levels.

Conclusions:

Manure-related H2S intoxication has high mortality but can have surprisingly favorable outcomes.
H2S may protect against hypoxic injury by inducing a suspended animation-like state.
Further research into H2S's protective effects in humans is warranted.