Outcome after hydrogen sulphide intoxication
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Updated: Mar 23, 2026

A Sensitive Visual Method for the Detection of Hydrogen Sulfide Producing Bacteria
Published on: June 27, 2022
Eline A Q Mooyaart1, Egbert L G Gelderman1, Maarten W Nijsten2
1Department of Anesthesiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Aim:
Hydrogen sulphide (H2S) intoxication in man is frequently associated with a fatal outcome. In small animal models hydrogen sulphide has demonstrated profound protection against hypoxia. No reports that focus on a potential protective effect in humans have been published.
Methods:
The frequency and outcome of a large cohort of hydrogen sulphide intoxications is described.
Results:
From 1980 until 2013, 35 accidents totalling 56 victims occurred of whom at least 24 (43%) survived. Of the 8 patients with documented cardiopulmonary resuscitation on the scene, 6 (75%) survived. In some of these cases with good outcome the exposure time to very high hydrogen sulphide levels before extraction and resuscitation was more than 45min.
Conclusion:
Manure related hydrogen sulphide intoxication is associated with a high mortality, although in some cases, recovery appears to be far more favourable than the initial presentation would suggest. Possibly protection from hypoxic injury due to induction of a suspended animation-like state by hydrogen sulphide may be responsible.
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