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Updated: Mar 23, 2026

Diffusion Imaging in the Rat Cervical Spinal Cord
Published on: April 7, 2015
Conceptual Foundations of Diffusion in Magnetic Resonance
Cheng Guan Koay1, Evren Özarslan2
1Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705.
Abstract:
A thorough review of the q-space technique is presented starting from a discussion of Fick's laws. The work presented here is primarily conceptual, theoretical and hopefully pedagogical. We offered the notion of molecular concentration to unify Fick's laws and diffusion MRI within a coherent conceptual framework. The fundamental relationship between diffusion MRI and the Fick's laws are carefully established. The conceptual and theoretical basis of the q-space technique is investigated from first principles.
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