A disruptive sequencer meets disruptive publishing
Related Experiment Video
Updated: Mar 23, 2026

Novel Sequence Discovery by Subtractive Genomics
Published on: January 25, 2019
Nick Loman1, Sarah Goodwin2, Hans Jansen3
1Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK.
Abstract:
Nanopore sequencing was recently made available to users in the form of the Oxford Nanopore MinION. Released to users through an early access programme, the MinION is made unique by its tiny form factor and ability to generate very long sequences from single DNA molecules. The platform is undergoing rapid evolution with three distinct nanopore types and five updates to library preparation chemistry in the last 18 months. To keep pace with the rapid evolution of this sequencing platform, and to provide a space where new analysis methods can be openly discussed, we present a new F1000Research channel devoted to updates to and analysis of nanopore sequence data.
Related Concept Videos
Next-generation Sequencing
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
Maxam-Gilbert Sequencing
Challenges of the Maxam-Gilbert Method
The...
Sanger Sequencing
Viral Recombination
Viral Mutations
Conservative Site-specific Recombination and Phase Variation
The recognition sites for Cre recombinase called LoxP...

