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Label-free fluorescence detection of microRNA based on target induced adenosine2-coralyne-adenosine2 formation
Jun-Jie Li1, Qiang Xi, Wen-Fang Du
1State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China. rqyu@hnu.edu.cn jianhuijiang@hnu.edu.cn.
The Analyst
|March 22, 2016
Abstract:
This study develops a simple and label-free biosensor for sensitive and selective detection of microRNA (miRNA) based on the formation of the adenosine2-coralyne-adenosine2 complex mediated by miRNA-specific polyadenosine extension.

