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Thimerosal-Preserved Hepatitis B Vaccine and Hyperkinetic Syndrome of Childhood

David A Geier1,2, Janet K Kern3,4, Brian S Hooker5,6

  • 1Institute of Chronic Illnesses, Inc., Silver Spring, MD 20905, USA. davidallengeier@comcast.net.

Brain Sciences
|March 22, 2016
PubMed

Insights

Exposure to mercury from Thimerosal-containing vaccines (TCVs) in early infancy is linked to a higher risk of Hyperkinetic Syndrome of Childhood (HKSoC). Increased organic mercury exposure from Thimerosal-preserved hepatitis B vaccines (TM-HepB) correlates with HKSoC diagnosis.

Area of Science:

  • Pediatric Neurology
  • Environmental Toxicology
  • Vaccine Safety Research

Background:

  • Hyperkinetic Syndrome of Childhood (HKSoC) involves inattention, hyperactivity, and impulsivity.
  • HKSoC is often diagnosed under broader Attention-Deficit and Disruptive Behavior Disorders categories.
  • Previous research suggests mercury (Hg) exposure may be a risk factor for HKSoC.

Purpose of the Study:

  • To investigate the toxicological effects of organic mercury exposure from Thimerosal-containing vaccines (TCVs).
  • To assess the relationship between Thimerosal-preserved hepatitis B vaccine (TM-HepB) exposure and the risk of HKSoC diagnosis.
  • To test the hypothesis that increased organic-Hg exposure impacts HKSoC risk.

Main Methods:

  • Utilized the Vaccine Safety Datalink database for a hypothesis testing study.
  • Examined exposure levels and timing of TM-HepB in the first six months of life.
  • Compared HKSoC diagnosis rates between exposed infants and control groups.

Main Results:

  • Infants diagnosed with HKSoC showed significantly higher exposure to organic-Hg from TM-HepB within the first month (OR=1.45).
  • Increased risk persisted for exposure within the first two months (OR=1.43) and six months (OR=4.51).
  • Higher organic-Hg exposure from TM-HepB doses was associated with elevated odds of HKSoC diagnosis.

Conclusions:

  • Findings suggest a heightened risk of HKSoC diagnosis with increased organic-Hg exposure from TCVs.
  • The timing and dosage of TM-HepB exposure appear to influence the risk of HKSoC.
  • This study supports a potential link between mercury exposure from vaccines and hyperkinetic disorders in children.

Keywords:
ADHDHyperkinetic syndrome of childhoodThimerosalneurodevelopmental disorder

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