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Amyloid Fibrils

Amyloid Fibrils

Amyloid Fibrils

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins. Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils.
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...

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Related Experiment Video

Updated: Mar 23, 2026

Visualizing Axonal Growth Cone Collapse and Early Amyloid β Effects in Cultured Mouse Neurons

Visualizing Axonal Growth Cone Collapse and Early Amyloid β Effects in Cultured Mouse Neurons

Published on: October 30, 2018

Nerve Hypertrophy in Primary Amyloidosis

Maria Rasenack¹, Anne-Katrin Proebstel¹, Ioanna M Athanasopoulou¹

¹Department of Neurology, Basel University Hospital, Basel, Switzerland.

|March 22, 2016

Summary

No abstract available in PubMed .

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