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Immunocytochemical localization of serotonin in the pineal gland
Microscopia Electronica Y Biologia Celular : Organo Oficial De Las Sociedades Latinoamericana De Microscopia Electronica E Iberoamericana De Biologia Celular
|June 1, 1989
Abstract:
The localization of serotonin (5HT) in the rat pineal gland during daylight conditions was investigated by light and electron microscopy using a polyclonal antibody to 5HT and the immunocytochemical method of peroxidase-antiperoxidase (PAP). Thin varicose 5HT fibers were found distributed in the gland at light microscopy level. Ultrastructural observations revealed the presence of terminal endings containing 5HT and localized mainly in the perivascular spaces, labeled with dense diaminobenzidine (DAB) deposits.