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[Current therapy of polyarticular forms of juvenile idiopathic arthritis]

A Hospach1, J M Rühlmann2, F Weller-Heinemann3

  • 1Zentrum für Pädiatrische Rheumatologie, Klinikum Stuttgart, Olgahospital, Kriegsbergstr. 62, 70174, Stuttgart, Deutschland. a.hospach@klinikum-stuttgart.de.

Zeitschrift Fur Rheumatologie
|March 23, 2016
PubMed

Insights

Juvenile idiopathic arthritis (JIA) is a common childhood rheumatic disease. This article reviews current treatments for the polyarticular form, including newer biologic disease-modifying antirheumatic drugs (DMARDs).

Area of Science:

  • Rheumatology
  • Pediatric Medicine
  • Pharmacology

Background:

  • Juvenile idiopathic arthritis (JIA) is the most prevalent rheumatic condition in children.
  • The polyarticular subtype affects about 20% of JIA patients, presenting significant morbidity and lasting effects.
  • Traditional treatments include steroids and conventional disease-modifying antirheumatic drugs (DMARDs).

Purpose of the Study:

  • To summarize current therapeutic strategies for polyarticular JIA.
  • To highlight recent advancements in JIA treatment, particularly biologic DMARDs.

Main Methods:

  • Review of existing literature on JIA treatment.
  • Analysis of therapeutic options, including conventional and biologic DMARDs.

Main Results:

  • The article provides an overview of established and emerging treatments for polyarticular JIA.
  • Biologic DMARDs represent a significant development in the last decade for managing JIA.

Conclusions:

  • Current therapy for polyarticular JIA involves a range of options.
  • The advent of biologic DMARDs has expanded treatment possibilities for JIA patients.

Keywords:
BiologicsDisease modifying antirheumatic drugsJuvenile idiopathic arthritisPolyarthritisTherapy

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