Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Probiotics01:22

Probiotics

50
Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
50
Proteomics01:33

Proteomics

10.1K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
10.1K
Bacterial Phylum Firmicutes01:27

Bacterial Phylum Firmicutes

1.2K
Firmicutes is a diverse phylum of Gram-positive bacteria characterized by a low GC content in their genomes. This phylum includes organisms with monoderm or diderm cell envelopes, highlighting a complex evolutionary history. Firmicutes comprises several major orders, including Lactobacillales, Clostridiales, and Bacillales, which exhibit remarkable diversity in their morphology, metabolism, and ecological roles.The order Lactobacillales includes lactic acid bacteria, which are fermentative...
1.2K
Operons02:09

Operons

55.6K
Prokaryotes can control gene expression through operons—DNA sequences consisting of regulatory elements and clustered, functionally related protein-coding genes. Operons use a single promoter sequence to initiate transcription of a gene cluster (i.e., a group of structural genes) into a single mRNA molecule. The terminator sequence ends transcription. An operator sequence, located between the promoter and structural genes, prohibits the operon’s transcriptional activity if bound by...
55.6K
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

830
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
830
Inducible Operons: lac Operon01:25

Inducible Operons: lac Operon

2.6K
The lac operon in Escherichia coli is a model for understanding inducible gene regulation and metabolic flexibility. It integrates local control by lactose and global regulation through catabolite repression, enabling E. coli to preferentially metabolize glucose when available and switch to lactose utilization when glucose is scarce.Structure and Function of the lac OperonThe lac operon contains three structural genes: lacZ (β-galactosidase), lacY (lactose permease), and lacA...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Municipal Solid Waste (MSW)-Compost Amendment Increases Diversity, Functional Activities, and Network Connectivity of a Vineyard Soil Microbiota.

Microorganisms·2026
Same author

GPCS Stratification of Exercise-Induced Gut Microbiota and Metabolome Remodeling in IBS: An Exploratory Multi-Omics Study.

Nutrients·2026
Same author

Carrot flour-enriched pasta with <i>in vitro</i> antioxidant activity and capacity of modulating inflammatory pathways in human colon cell model.

Frontiers in nutrition·2026
Same author

Cheeseomics of Grana Padano PDO cheese: Microbial diversity and flavour profiles compared to non-PDO cheeses.

International journal of food microbiology·2026
Same author

Functional attributes of Propionibacterium freudenreichii and phenotypic shift during fermentation in a faba bean-based model medium.

International journal of food microbiology·2026
Same author

Impact of fermentation regime and metabolically defined LAB consortia on sourdough bread nutritional and volatile composition.

Food chemistry·2026
Same journal

Identification of Novel Interacting Proteins of FUZ and GPR161.

Proteomics·2026
Same journal

Light-Induced Proteomic Changes in Pseudomonas aeruginosa Biofilms.

Proteomics·2026
Same journal

Decade-Resolved Proteomic Profiling of Gastric Cancer FFPE Archives: Evaluating Storage-Associated Shifts and Signal Stability Over 50 Years.

Proteomics·2026
Same journal

Proteome-Scale Mining of Metal-Associated Proteins of Monkeypox Virus.

Proteomics·2026
Same journal

Optimized Sample Handling Minimizes Peptide Adsorption to Plastics to Enable High Sensitivity Evosep Based Chemical Proteomics.

Proteomics·2026
Same journal

Toward Predicting Pandemic Potential: A Comparative Analysis of Virus-Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System.

Proteomics·2026
See all related articles

Related Experiment Video

Updated: Mar 23, 2026

Evaluation of Microbial Safety of Dairies using Bacterial Proteomic Profiling via MALDI Approach
09:31

Evaluation of Microbial Safety of Dairies using Bacterial Proteomic Profiling via MALDI Approach

Published on: October 7, 2025

722

Functional proteomics within the genus Lactobacillus.

Maria De Angelis1, Maria Calasso1, Noemi Cavallo1

  • 1Department of Soil, Plant and Food Science, University of Bari Aldo Moro, Bari, Italy.

Proteomics
|March 23, 2016
PubMed
Summary
This summary is machine-generated.

This review explores Lactobacillus proteomics and metaproteomics, revealing how these bacteria adapt their protein profiles to diverse environments. Understanding these adaptations is key for optimizing their use in food and probiotics.

Keywords:
Environmental metabolic adaptationLactobacillusMicrobiologySecretomeStress response

More Related Videos

Subtyping of Campylobacter jejuni ssp. doylei Isolates Using Mass Spectrometry-based PhyloProteomics MSPP
09:43

Subtyping of Campylobacter jejuni ssp. doylei Isolates Using Mass Spectrometry-based PhyloProteomics MSPP

Published on: October 30, 2016

9.1K
Author Spotlight: Methods for Electroporation and Transformation Confirmation in Limosilactobacillus reuteri DSM20016
11:04

Author Spotlight: Methods for Electroporation and Transformation Confirmation in Limosilactobacillus reuteri DSM20016

Published on: June 23, 2023

5.2K

Related Experiment Videos

Last Updated: Mar 23, 2026

Evaluation of Microbial Safety of Dairies using Bacterial Proteomic Profiling via MALDI Approach
09:31

Evaluation of Microbial Safety of Dairies using Bacterial Proteomic Profiling via MALDI Approach

Published on: October 7, 2025

722
Subtyping of Campylobacter jejuni ssp. doylei Isolates Using Mass Spectrometry-based PhyloProteomics MSPP
09:43

Subtyping of Campylobacter jejuni ssp. doylei Isolates Using Mass Spectrometry-based PhyloProteomics MSPP

Published on: October 30, 2016

9.1K
Author Spotlight: Methods for Electroporation and Transformation Confirmation in Limosilactobacillus reuteri DSM20016
11:04

Author Spotlight: Methods for Electroporation and Transformation Confirmation in Limosilactobacillus reuteri DSM20016

Published on: June 23, 2023

5.2K

Area of Science:

  • Microbiology
  • Proteomics
  • Food Science

Background:

  • Lactobacillus species are crucial in fermented foods and probiotics.
  • Their functionality relies on enzymes and metabolites, influenced by processing conditions.
  • Genomic analysis provides insights, but proteomic diversity remains key to understanding adaptation.

Purpose of the Study:

  • To review novel functional proteomics and metaproteomics of Lactobacillus species.
  • To elucidate proteome diversity, regulation, and adaptation mechanisms.
  • To provide a comprehensive understanding of Lactobacillus niche adaptation.

Main Methods:

  • Review of existing proteomic and metaproteomic case studies.
  • Analysis of genomic diversity to complement proteomic findings.
  • Focus on functional proteomics to understand protein roles.

Main Results:

  • Lactobacillus strains exhibit significant proteome diversity.
  • Adaptability of metabolic pathways (carbohydrate, pyruvate, amino acid metabolism, protein synthesis) to various conditions was illustrated.
  • Modulation of protein levels allows survival and growth in different ecological niches.

Conclusions:

  • Proteomics is essential for understanding Lactobacillus adaptation and regulation.
  • Lactobacilli dynamically adjust protein expression for niche survival.
  • Metabolic pathways are switched on/off, altering strain behavior and functionality.