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Cinnamon users with prediabetes have a better fasting working memory: a cross-sectional function study.

Mark L Wahlqvist1, Meei-Shyuan Lee2, Jiunn-Tay Lee3

  • 1School of Public Health, National Defense Medical Center, Taipei, Taiwan, ROC; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan, ROC; Monash Asia Institute, Monash University, Melbourne, VIC, Australia; Fuli institute of Food Science and Nutrition, Zhejiang University, Zhejiang, China.

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Summary

Cinnamon consumption may improve working memory in individuals with prediabetes, independent of diet quality or insulin resistance. This study suggests culinary herbs could play a role in cognitive health for this population.

Keywords:
Body fatnessCinnamonCognitionGingerInsulin resistanceTurmeric

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Area of Science:

  • Nutrition Science
  • Cognitive Neuroscience
  • Metabolic Health

Background:

  • Prediabetes is associated with impaired working memory (WM).
  • Culinary herbs and spices are explored for their potential to mitigate insulin resistance (IR) and enhance cognitive function.
  • Understanding the relationship between dietary components and cognitive health in prediabetes is crucial.

Purpose of the Study:

  • To investigate the hypothesis that culinary herbs and spices can decrease insulin resistance (IR) and improve working memory (WM) in individuals with prediabetes.
  • To determine the association between the use of specific culinary herbs (cinnamon, ginger, curry) and WM performance.
  • To identify other contributing factors to WM in this population, including diet, body composition, and metabolic markers.

Main Methods:

  • A cross-sectional study involving healthy adults aged 60 years and older with prediabetes.
  • Assessment of dietary habits using a food frequency questionnaire, with a focus on culinary herb intake.
  • Measurement of body composition, fasting glucose, insulin, and evaluation of working memory and Mini-Mental State Examination (MMSE) scores.
  • Linear regression analysis was employed to estimate the contributions of various factors to WM.

Main Results:

  • Cinnamon users exhibited significantly better working memory compared to non-users (P < .001).
  • Cinnamon use was a significant predictor of WM, even after adjusting for sociodemographic variables, total fat mass, and MMSE scores.
  • Neither ginger nor curry usage demonstrated a significant association with improved WM.
  • Education level and MMSE scores were also significant predictors of WM.

Conclusions:

  • Cinnamon usage is independently associated with enhanced working memory in individuals with untreated prediabetes.
  • The positive effect of cinnamon on WM in this context is not explained by overall dietary quality or insulin resistance.
  • Further research into the specific mechanisms by which cinnamon impacts cognitive function in prediabetes is warranted.