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Cardiovascular disease and hypertension in sub-Saharan Africa: burden, risk and interventions
Francesco Paolo Cappuccio1, Michelle Avril Miller2
1Division of Health Sciences (Mental Health and Wellbeing), WHO Collaborating Centre, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK. f.p.cappuccio@warwick.ac.uk.
Insights
Cardiovascular disease is rising in sub-Saharan Africa due to urbanization. High blood pressure management is suboptimal, straining resources and impacting economies.
Area of Science:
- Public Health
- Cardiology
- Global Health
Background:
- Cardiovascular diseases (CVD), including stroke and heart failure, are prevalent in sub-Saharan Africa.
- Urbanization is accelerating the incidence of ischaemic heart disease and metabolic disorders in the region.
- Low- and middle-income countries bear a disproportionate burden of cardiovascular deaths.
Purpose of the Study:
- To highlight the critical issue of high blood pressure (hypertension) as the primary risk factor for CVD in sub-Saharan Africa.
- To analyze the deficiencies in the prevention, detection, treatment, and control of hypertension in the region.
- To underscore the substantial economic consequences of suboptimal hypertension management.
Main Methods:
- This study is a review of the current state of cardiovascular disease and hypertension in sub-Saharan Africa.
- Analysis of factors contributing to the suboptimal management of hypertension.
- Assessment of the economic impact of cardiovascular disease and hypertension.
Main Results:
- High blood pressure is the most significant underlying risk factor for cardiovascular disease in sub-Saharan Africa.
- Prevention, detection, treatment, and control of hypertension are inadequate and inefficient.
- Key challenges include resource limitations, weak healthcare systems, lack of population-level prevention, unsustainable drug therapy, and poor patient compliance.
Conclusions:
- Urgent and comprehensive strategies are needed to improve hypertension control in sub-Saharan Africa.
- Addressing resource limitations and strengthening healthcare systems are crucial for effective CVD prevention and management.
- Suboptimal hypertension management leads to significant economic losses and increased demand on healthcare services.
Abstract:
Cardiovascular disease, including stroke, heart failure and kidney disease, has been common in sub-Saharan Africa for many years, and rapid urbanization is causing an upsurge of ischaemic heart disease and metabolic disorders. At least two-thirds of cardiovascular deaths now occur in low- and middle-income countries, bringing a double burden of disease to poor and developing world economies. High blood pressure (or hypertension) is by far the commonest underlying risk factor for cardiovascular disease. Its prevention, detection, treatment and control in sub-Saharan Africa are haphazard and suboptimal. This is due to a combination of lack of resources and health-care systems, non-existent effective preventive strategies at a population level, lack of sustainable drug therapy, and barriers to complete compliance with prescribed medications. The economic impact for loss of productive years of life and the need to divert scarce resources to tertiary care are substantial.
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Physiological Factors:
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Hypertension I: Introduction

