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Updated: Mar 23, 2026

10:34
FRET Microscopy for Real-time Monitoring of Signaling Events in Live Cells Using Unimolecular Biosensors
Published on: August 20, 2012
23.9K
Facile creation of FRET systems from a pH-responsive AIE fluorescent vesicle
Xing Wang1, Yanyu Yang, Yunfei Zuo
1Beijing National Laboratory for Molecular Sciences, State Key Laboratory of Polymer Physics & Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. dcwu@iccas.ac.cn.
Abstract:
We demonstrate a facile approach to constructing aggregation induced emission (AIE) fluorescent vesicles assembled using a PEG-POSS-(TPE)7 polymer. The narrow wall thickness provides an ideal confined space for creating fluorescence resonance energy transfer (FRET) systems between TPE donors and encapsulated FITC or DOX acceptors.

