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A Ligated Intestinal Loop Model in Anesthetized Specific Pathogen Free Chickens to Study Clostridium Perfringens Virulence
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Recent breakthroughs have unveiled the many knowledge gaps in Clostridium perfringens-associated necrotic enteritis

F Van Immerseel1, U Lyhs2, K Pedersen2

  • 1a Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine , Ghent University , Merelbeke , Belgium.

Avian Pathology : Journal of the W.V.P.A
|March 23, 2016
PubMed
Abstract

No abstract available in PubMed .

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Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...
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