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Citrate-Based Biomaterials and Their Applications in Regenerative Engineering
Richard T Tran1, Jian Yang1, Guillermo A Ameer2
1Department of Biomedical Engineering, Materials Research Institute, and The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802.
Abstract:
Advances in biomaterials science and engineering are crucial to translating regenerative engineering, an emerging field that aims to recreate complex tissues, into clinical practice. In this regard, citrate-based biomaterials have become an important tool owing to their versatile material and biological characteristics including unique antioxidant, antimicrobial, adhesive, and fluorescent properties. This review discusses fundamental design considerations, strategies to incorporate unique functionality, and examples of how citrate-based biomaterials can be an enabling technology for regenerative engineering.
