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Related Concept Videos

Arboviral Encephalitis01:25

Arboviral Encephalitis

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Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
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Cytomegalovirus Disease01:27

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Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
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Related Experiment Video

Updated: Mar 23, 2026

Establishing Mouse Models for Zika Virus-induced Neurological Disorders Using Intracerebral Injection Strategies: Embryonic, Neonatal, and Adult
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Zika Virus Infection and Microcephaly.

J Gordon Millichap1

  • 1Division of Neurology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Departments of Pediatrics and Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Pediatric Neurology Briefs
|March 23, 2016
PubMed
Summary
This summary is machine-generated.

Brazil investigated microcephaly cases potentially linked to Zika virus infection during pregnancy. A registry was established to track these cases for further study.

Keywords:
Aedes mosquitoesBrazilMicrocephalyZika virus

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Area of Science:

  • Public Health
  • Infectious Diseases
  • Neurology

Background:

  • Microcephaly is a serious congenital condition.
  • Zika virus infection during pregnancy was suspected as a cause.
  • Brazil's Ministry of Health initiated an investigation.

Purpose of the Study:

  • To investigate the association between microcephaly and Zika virus infection in pregnant women.
  • To establish a registry for microcephaly cases in Brazil.

Main Methods:

  • A Task Force was established by the Brazil Ministry of Health.
  • Data collection focused on pregnant women with suspected Zika virus infection.
  • A registry was created to document microcephaly cases.

Main Results:

  • The study aimed to confirm the link between Zika virus and microcephaly.
  • The registry provided a framework for case identification and tracking.

Conclusions:

  • The investigation sought to understand the epidemiological link between Zika virus and microcephaly.
  • Public health surveillance and data collection were crucial.