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Developing a Salivary Antibody Multiplex Immunoassay to Measure Human Exposure to Environmental Pathogens
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Detection of Vaccine-Induced Antibodies to Ebola Virus in Oral Fluid
Teresa Lambe1, Tommy Rampling1, Dhan Samuel2
1Jenner Institute , University of Oxford.
Abstract:
Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in a minimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875.
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