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Two new eunicellin diterpenoids from the East China Sea gorgonian Muricella sp
Chuan Zhao1, Jia Wang1, De-Jun Jin2
1a Research Center of Basic Medical Sciences, Tianjin Key Laboratory on Technologies Enabling Development Clinical Therapeutics and Diagnostics (Theranostics) , School of Pharmacy, Tianjin Medical University , Tianjin 300070 , China.
Abstract:
A phytochemical investigation on gorgonian Muricella sp. from East China Sea resulted in the isolation of eight eunicellin diterpenoids including two new ones, muricellins A-B (1, 2). Chemical structures of these compounds were elucidated by spectroscopic techniques (1D and 2D NMR and MS) and by comparison with data reported in the literature. Anti-rheumatoid arthritis activities of 1, 3, 4, and 6 have been evaluated.

