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Biodegradable poly(ethylene glycol) methyl ether acrylate-b-poly(l-lysine)-b-poly(l-histidine) triblock

Renjith P Johnson1, Saji Uthaman2, Johnson V John1

  • 1BK21 PLUS Center for Advanced Chemical Technology, Department of Polymer Science and Engineering, Pusan National University, Pusan 609-735, Republic of Korea.

Journal of Controlled Release : Official Journal of the Controlled Release Society
|March 24, 2016
PubMed
Abstract

No abstract available in PubMed .

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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
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