[Epidemiology of intussusception related hospitalizations in children aged <2 years in Suzhou, 2007-2013]
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Updated: Mar 23, 2026

Surgical Correction for Pediatric Epiblepharon and Trichiasis
Published on: July 8, 2025
Pengwei Cui1, Na Liu1, Jingxin Li1
1Department for Viral Diarrhea, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Insights
Intussusception hospitalization incidence is high in children under two years old in Suzhou. Establishing surveillance is crucial for monitoring rotavirus vaccine safety in this age group.
Area of Science:
- Pediatric Gastroenterology
- Epidemiology
- Public Health
Background:
- Intussusception is a common cause of intestinal obstruction in infants and young children.
- Understanding the epidemiological and clinical patterns of intussusception is vital for effective management and prevention strategies.
Purpose of the Study:
- To investigate the epidemiological and clinical characteristics of intussusception hospitalizations in children younger than two years.
- To provide data for evaluating the safety of rotavirus vaccines.
Main Methods:
- Retrospective collection of clinical and demographic data for children under two years old hospitalized with intussusception between January 2007 and August 2013.
- Analysis of incidence, age distribution, seasonality, and clinical features of these cases.
Main Results:
- A total of 594 hospitalizations for intussusception were recorded in children under two years old, with no deaths.
- The crude incidence was 57.3 per 100,000 for children under two and 100.6 per 100,000 for those under one year.
- Vomiting, abdominal mass, and bloody stool were the most common symptoms; ileocolic intussusception was most frequent.
Conclusions:
- The incidence of hospitalized intussusception among children under two years in Suzhou is notably high.
- An active surveillance system is recommended to gather baseline data for rotavirus vaccine safety assessments.
Objective:
To understand the epidemiological and clinical characteristics of <2 years old children hospitalized due to intussusceptions.
Methods:
Clinical and demographic data of <2 years old children hospitalized due to intussusception between January 2007 and August 2013 were retrospectively collected in Affiliated Children' s Hospital of Soochow University in Suzhou. The incidence data, age distribution, seasonality and clinical characteristics of hospitalized intussusceptions cases were analyzed.
Results:
A total of 594 intussusception-related hospitalizations were identified during this period in children aged <2 years, no death occurred. The crude incidence of hospitalized intussusception was 57.3 per 100,000 in children aged <2 years (95%CI: 52.8-62.1), and 100.6 per 100,000 in children aged <1 year (95%CI: 92.1-109.8). The male to female ratio was 1.90:1. Up to 85.4% (507/594) of the cases were aged <1 year, and 66.2% (393/594) of the cases were aged 3-8 months. The incidence peaked in age group 5-8 months. The median age of the cases was 6.8 months (QR=4.4), and increased from 6.3 months (QR=4.2) in 2007 to 7.3 months (QR=4.0) in 2013. No obvious seasonality was observed. Main symptoms or signs included vomiting (83.2%, 494/594), abdominal mass (81.1%, 482/594), and bloody stool (64.5%, 383/594). Abdominal ultrasonic testing was the most frequently used diagnostic approach (98.7%, 586/594). Up to 86.2% (512/594) of patients were successfully treated by surgical intervention. The main sites for acute intussusception in children aged <2 years were ileocolic (34.5%, 183/530), ileo-ileo (30.8%, 163/530) or ileo-ileo-colic (27.9%, 148/530).
Conclusion:
The incidence of hospitalized intussusception in children aged <2 years was high in Suzhou. It is necessary to establish an active surveillance system to provide baseline data for the evaluation of rotavirus vaccine safety.
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