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A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
Cardiorespiratory Fitness and Atherosclerosis: Recent Data and Future Directions
Emile Mehanna1,2, Anne Hamik1,3,2, Richard A Josephson4,5
1Division of Cardiovascular Medicine, Harrington Heart & Vascular Institute, University Hospitals Health System, Mailstop LKS 5038, 11100 Euclid Avenue, Cleveland, OH, 44106-5038, USA.
Abstract:
Historically, the relationship between exercise and the cardiovascular system was viewed as unidirectional, with a disease resulting in exercise limitation and hazard. This article reviews and explores the bidirectional nature, delineating the effects, generally positive, on the cardiovascular system and atherosclerosis. Exercise augments eNOS, affects redox potential, and favorably affects mediators of atherosclerosis including lipids, glucose homeostasis, and inflammation. There are direct effects on the vasculature as well as indirect benefits related to exercise-induced changes in body composition and skeletal muscle. Application of aerobic exercise to specific populations is described, with the hope that this knowledge will move the science forward and improve individual patient outcome.
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