Related Experiment Video
Updated: Mar 23, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Coronary Thrombosis without Dissection following Blunt Trauma
Archana Sinha1, Michael Sibel2, Peter Thomas3
1Division of Cardiovascular Disease, Saint Luke's University Health Network, Bethlehem, PA 18015, USA.
Chest trauma can cause coronary thrombosis and ST-elevation myocardial infarction (STEMI). This case report details blunt trauma leading to coronary thrombosis without dissection or atherosclerosis, as confirmed by intravascular ultrasound (IVUS).
Area of Science:
- Cardiology
- Trauma Surgery
- Medical Imaging
Background:
- Blunt chest trauma can rarely cause coronary thrombosis and ST-elevation myocardial infarction (STEMI).
- Previous cases involving intravascular ultrasound (IVUS) implicated coronary artery dissection as the cause.
- Findings on angiography often mimic spontaneous plaque rupture due to atherosclerosis.
Purpose of the Study:
- To report the first case of blunt trauma-associated coronary thrombosis without underlying atherosclerosis or coronary dissection.
- To document the findings using intravascular ultrasound (IVUS) imaging.
Main Methods:
- Case report presentation.
- Diagnostic coronary angiography.
- Intravascular ultrasound (IVUS) imaging for detailed coronary artery assessment.
Main Results:
- The patient experienced coronary thrombosis and ST-elevation myocardial infarction (STEMI) following blunt chest trauma.
- Coronary angiography showed complete epicardial coronary occlusion with thrombus.
- Intravascular ultrasound (IVUS) imaging revealed no evidence of coronary artery dissection or underlying atherosclerotic disease.
Conclusions:
- Blunt chest trauma can lead to coronary thrombosis and STEMI through mechanisms other than coronary dissection or atherosclerosis.
- IVUS imaging is crucial for accurately diagnosing the etiology of coronary thrombosis in trauma patients.
- This case expands the understanding of rare cardiovascular complications following chest trauma.
More Related Videos
Related Concept Videos
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome III: Diagnostic Studies
Coronary Artery Disease II: Pathophysiology
Acute Coronary Syndrome IV: Interprofessional Care
Flail Chest-I
Flail chest is a severe and potentially life-threatening condition characterized by the fracture of three or more adjacent ribs in multiple places. It is most commonly caused by direct impacts and trauma, such as motor vehicle accidents or injuries from a steering wheel impact. It can also occur due to falls in elderly individuals with osteoporosis, or assaults involving sharp objects.
Pathophysiology
The pathophysiology of flail chest is complex, involving fractures of...

