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Related Concept Videos

Infertility in Females01:28

Infertility in Females

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Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
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Related Experiment Video

Updated: Mar 23, 2026

Author Spotlight: A Reproductive Hysteroscopy Approach for Complete Endometrial Polyp Removal and Enhanced Endometrial Receptivity
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Endometrial scratching for subfertility: everyone's doing it.

S Lensen1, L Sadler2, C Farquhar3

  • 1Department of Obstetrics and Gynaecology, University of Auckland, Auckland, New Zealand s.lensen@auckland.ac.nz.

Human Reproduction (Oxford, England)
|March 25, 2016
PubMed
Summary
This summary is machine-generated.

Eighty-three percent of clinicians surveyed recommend endometrial scratching for women undergoing IVF, particularly those with recurrent implantation failure. This practice is common, but further research may refine its benefits and optimal use.

Keywords:
IVFendometrial biopsyendometrial injuryendometrial pipelleendometrial scratchingrecurrent failurerecurrent implantation failure

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Area of Science:

  • Reproductive Medicine
  • Infertility Treatments
  • Clinical Practice Surveys

Background:

  • Endometrial scratching is a proposed technique to enhance IVF implantation rates.
  • Existing trial data suggest benefits, but optimal patient selection and effect size require further clarification.

Purpose of the Study:

  • To determine the proportion of clinicians in Australia, New Zealand, and the UK offering or recommending endometrial scratching for subfertility.
  • To understand current clinical practices and perceptions regarding endometrial scratching.

Main Methods:

  • A cross-sectional online survey was distributed to fertility clinics across Australia, New Zealand, and the UK.
  • Data were collected from 143 clinicians, nurses, and embryologists between August and October 2015.

Main Results:

  • 83% of surveyed clinicians recommend endometrial scratching prior to IVF.
  • 92% of these recommend it for recurrent implantation failure (RIF), while 6% recommend it for all IVF patients.
  • Most respondents believe it's beneficial for RIF but not for first IVF cycles; luteal phase scratching is most common.

Conclusions:

  • Endometrial scratching is widely recommended by clinicians, especially for RIF.
  • Clinical adoption appears high, but further research is needed to confirm benefits and identify optimal patient subgroups.
  • Findings are generalizable to similar international fertility settings.