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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
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Quantification of Left Ventricular Function With Premature Ventricular Complexes Reveals Variable Hemodynamics.

Francisco Contijoch1, Kelly Rogers2, Hannah Rears2

  • 1From the Department of Bioengineering (F.C.), Cardiovascular Division, Department of Medicine (K.R., E.S.Z., G.E.S., F.E.M., Y.H.), Department of Radiology (H.R., M.S., P.Y., W.R.T.W.), and Department of Surgery (J.G., R.C.G.), University of Pennsylvania, Philadelphia; and Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (P.K.). yuchi.han@uphs.upenn.edu.

Circulation. Arrhythmia and Electrophysiology
|March 25, 2016
PubMed
Summary
This summary is machine-generated.

Real-time cardiovascular magnetic resonance imaging reveals how premature ventricular complexes (PVCs) impact heart function. This technique quantifies hemodynamic differences caused by various PVC patterns, offering new insights into their effects.

Keywords:
cardiac arrhythmiasechocardiographymagnetic resonance imagingstroke volumeventricular premature complexes

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Area of Science:

  • Cardiology
  • Medical Imaging
  • Physiology

Background:

  • Premature ventricular complexes (PVCs) are common and can affect ventricular function.
  • Existing imaging methods inadequately assess PVCs' impact on left ventricular function.

Purpose of the Study:

  • To evaluate the hemodynamic effects of different premature ventricular complex (PVC) patterns.
  • To assess the utility of 2D real-time cardiovascular magnetic resonance imaging (CMR) in analyzing PVCs.

Main Methods:

  • Utilized 2D real-time CMR with ECG synchronization in 15 subjects with frequent PVCs.
  • Quantified global ventricular volumes and hemodynamic parameters (preload, stroke volume, ejection fraction) for various beat types.
  • Categorized beats based on RR duration and analyzed different ectopy patterns (isolated PVCs, bigeminy, trigeminy, interpolated PVCs).

Main Results:

  • Demonstrated distinct hemodynamic contributions from different PVC patterns.
  • Showcased differences in preload, stroke volume, and ejection fraction based on PVC timing and type.
  • Quantified average hemodynamic function per subject, correlated with PVC frequency.

Conclusions:

  • Real-time CMR effectively reveals the differential hemodynamic impact of PVCs.
  • This imaging approach provides a detailed understanding of PVCs' contribution to cardiovascular function.