Abnormal tyrosine metabolism in chronic cluster headache

Giovanni D'Andrea1, Massimo Leone2, Gennaro Bussone2

  • 11 Research and Innovation (R&I) s.r.l., Italy.

Summary

Chronic cluster headache patients exhibit altered tyrosine metabolism, with higher levels of dopamine, noradrenaline, and tyramine, and lower levels of octopamine and synephrine compared to controls. These biochemical changes may predispose individuals to chronic cluster headache.

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