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Published on: September 21, 2021
Aortic complications following pediatric heart transplantation: A case series and review
Sean M Lang1, Elizabeth A Frazier1, R Thomas Collins2
1Arkansas Children's Hospital, Little Rock, Arkansas, USA; Department of Pediatrics, The University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Insights
Aortic complications are rare but serious after pediatric heart transplants. Identifying risk factors is crucial for preventing these catastrophic events in young heart recipients.
Area of Science:
- Cardiology
- Pediatric Surgery
- Transplantation Medicine
Background:
- Pediatric orthotopic heart transplantation (HT) is a life-saving procedure for end-stage heart failure.
- Aortic complications following pediatric HT are infrequent but associated with severe outcomes.
Observation:
- This study details three cases of major aortic complications in 329 pediatric heart transplants.
- The cases highlight the critical nature of aortic integrity post-transplantation.
Findings:
- Rare aortic complications after pediatric heart transplantation carry a high risk of catastrophic events.
- Analysis of these cases identifies key risk factors associated with aortic complications.
Implications:
- Understanding these risk factors can improve patient selection and surgical techniques.
- Proactive monitoring and management strategies may reduce the incidence and severity of aortic complications in pediatric HT recipients.
Abstract:
Aortic complications occur rarely after pediatric orthotopic heart transplantation, but are typically accompanied by catastrophic events. We describe the three cases of major aortic complications in our experience of 329 pediatric heart transplants. This case series and review highlight the important risk factors for aortic complications after heart transplantation.

