Related Experiment Video
Updated: Mar 23, 2026

08:59
Human Dupuytren's Ex Vivo Culture for the Study of Myofibroblasts and Extracellular Matrix Interactions
Published on: April 18, 2015
11.0K
Dupuytren's contracture in Ethiopia
A Gebereegziabher1, A Baraki1, Y Kebede1
11 Department of Plastic Reconstructive and Hand Surgery, ALERT Center, Addis Ababa, Ethiopia.
The Journal of Hand Surgery, European Volume
|March 26, 2016
Summary
Dupuytren
Area of Science:
- Orthopedics
- Dermatology
- Epidemiology
Background:
- Dupuytren's contracture is considered rare in African populations.
- Clinical observations suggest a higher prevalence in Ethiopia than previously reported.
Purpose of the Study:
- To investigate the occurrence and epidemiological characteristics of Dupuytren's contracture in Ethiopian patients.
- To identify potential risk factors associated with the condition in this demographic.
Main Methods:
- A case-control study involving 75 patients diagnosed with Dupuytren's contracture.
- Demographic data and risk factors were collected and compared to a control group.
Main Results:
- The male to female ratio was 18:1, with the little and ring fingers most commonly affected.
- A significant association was found with hypertension and alcohol consumption.
- Co-occurrence with fibromatosis of the feet and penis was noted in some patients.
Conclusions:
- Dupuytren's contracture appears more prevalent in Ethiopia than previously assumed.
- Hypertension and alcohol consumption are identified as potential risk factors in this population.

