Multidrug Resistant Shigella flexneri Infection Simulating Intestinal Intussusception.

Area of Science:

• Pediatric Infectious Diseases
• Microbiology
• Gastroenterology

Background:

• Shigella enteritis is a major cause of mortality and morbidity globally.
• Emerging multidrug resistance in Shigella species poses a significant public health threat.
• Constant monitoring of Shigella resistance patterns is crucial for effective treatment.

Observation:

• A case of segmental ileitis in an infant presented with symptoms mimicking intussusception.
• The ileitis was caused by non-ESBL producing multidrug-resistant Shigella flexneri.
• This specific Shigella strain exhibited resistance to multiple antibiotics.

Findings:

• Multidrug-resistant Shigella flexneri was identified as the causative agent of ileitis.
• The infant's condition clinically resembled intussusception.
• Effective treatment was achieved using ceftriaxone.

Implications:

• This case underscores the importance of considering resistant bacterial infections in pediatric gastrointestinal emergencies.
• Ceftriaxone can be an effective therapeutic option for non-ESBL producing multidrug-resistant Shigella flexneri infections.
• Further research into antimicrobial resistance patterns in Shigella is warranted to guide clinical practice.