Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Double-label and conventional deoxyglucose methods: a practical guide for the user.

C Redies1, A Gjedde

  • 1Department of Brain and Cognitive Sciences, Whitaker College, Massachusetts Institute of Technology, Cambridge 02139.

Cerebrovascular and Brain Metabolism Reviews
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mitochondrial DNA G13708A variation and multiple sclerosis: Is there an association?

Revue neurologique·2017
Same author

Behavioural effects of high fat diet in a mutant mouse model for the schizophrenia risk gene neuregulin 1.

Genes, brain, and behavior·2015
Same author

Cortical plasticity after cochlear implantation.

Neural plasticity·2013
Same author

Delayed response task performance as a function of age in cynomolgus monkeys (Macaca fascicularis).

Primates; journal of primatology·2013
Same author

Dopaminergic and clinical correlates of pathological gambling in Parkinson's disease: a case report.

Frontiers in behavioral neuroscience·2013
Same author

Low dopamine D5 receptor density in hippocampus in an animal model of attention-deficit/hyperactivity disorder (ADHD).

Neuroscience·2013

The autoradiographic deoxyglucose method maps brain activity but has a complex kinetic model. This review simplifies the deoxyglucose method for researchers, explaining its procedures and calculations for functional brain mapping.

Area of Science:

  • Neuroscience
  • Physiology

Background:

  • The autoradiographic deoxyglucose method is a common technique for visualizing functional brain activity in mammals.
  • While user-friendly, the method's underlying kinetic model is intricate and poses challenges for non-specialists.

Purpose of the Study:

  • To review the deoxyglucose kinetic model and its practical implications for researchers.
  • To provide a clear understanding of the deoxyglucose method for users without deep tracer kinetics knowledge.

Main Methods:

  • Discussion of single-label and double-label deoxyglucose approaches.
  • Detailed description of experimental procedures.
  • Explanation of calculations for qualitative and quantitative analyses.

Main Results:

Related Experiment Videos

  • The paper clarifies the complex kinetic model of the deoxyglucose method.
  • It details experimental protocols and calculation methods for functional brain mapping.

Conclusions:

  • This review aims to demystify the deoxyglucose method, making it more accessible for functional brain activity mapping.
  • It provides a comparative overview with alternative brain mapping techniques.