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Updated: Mar 23, 2026

Author Spotlight: Advancing Liver Regeneration Research through ALPPS Mouse Model
Published on: January 19, 2024
Preoperative Assessment and Optimization of the Future Liver Remnant
Pragatheeshwar Thirunavukarasu1, Thomas A Aloia1
1HPB Surgery Section, Department of Surgical Oncology, UT-MD Anderson Cancer Center, 1400 Herman Pressler Drive, Unit 1484, Houston, TX 77030, USA.
Abstract:
Liver resection of benign, primary, and metastatic tumors is challenging and places patients at risk for postoperative liver insufficiency. The magnitude of this risk largely depends on the volume and function of the future liver remnant (FLR). It is, therefore, critical that hepatobiliary surgeons are well versed in measurement of liver volume and function as well as various techniques for preoperative liver volume augmentation. The absolute volume of FLR required to avoid postoperative liver insufficiency depends on patient, disease, and anatomic factors. Rapid expansion of the FLR can safely be achieved with portal venous embolization of the contralateral liver segments.
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