Related Experiment Video
Updated: Mar 23, 2026
05:19
Practical Methodology of Cognitive Tasks Within a Navigational Assessment
Published on: June 1, 2015
14.1K
Cohort Profile: The Saguenay Youth Study (SYS)
Zdenka Pausova1, Tomas Paus2,3, Michal Abrahamowicz4
1Hospital for Sick Children and Departments of Physiology and Nutritional Science.
International Journal of Epidemiology
|March 29, 2016
Summary
The Saguenay Youth Study investigates cardiometabolic and brain diseases across generations. This research aims to understand disease origins and improve healthy life expectancy through extensive genetic and phenotypic data.
Area of Science:
- Genetics and Genomics
- Epidemiology
- Public Health
Background:
- Cardiometabolic and brain diseases pose significant public health challenges.
- Understanding their aetiology and trans-generational trajectories is crucial for prevention.
Purpose of the Study:
- To investigate the origins and progression of common cardiometabolic and brain diseases across two generations.
- To identify strategies for increasing healthy life expectancy.
Main Methods:
- Two-generational cohort study (1029 adolescents, 962 parents) from a founder population.
- Extensive phenotyping: 15-hour assessments including blood pressure, MRI, lipidomics, genome-wide genotyping, and epigenotyping.
- Comprehensive evaluation of cognition, mental health, lifestyle, and family environment.
Main Results:
- Rich dataset available for investigating disease aetiology and trans-generational patterns.
- Established a unique resource for studying common diseases in a founder population.
Conclusions:
- The Saguenay Youth Study provides a valuable resource for understanding disease development and promoting healthy aging.
- Data availability upon request facilitates further research into cardiometabolic and brain health.
Related Concept Videos
01:26Longitudinal Studies
649
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
649
02:20Longitudinal Research
13.6K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
13.6K
01:11Observational Studies
11.4K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
11.4K
01:30Community Based Intervention
574
Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
574
01:50Cross-Sectional Research
12.9K
In cross-sectional research, a researcher compares multiple segments of the population at the same time. If they were interested in people's dietary habits, the researcher might directly compare different groups of people by age. Instead of following a group of people for 20 years to see how their dietary habits changed from decade to decade, the researcher would study a group of 20-year-old individuals and compare them to a group of 30-year-old individuals and a group of 40-year-old...
12.9K
01:22Case Studies
13.8K
There are many research methods available to psychologists in their efforts to understand, describe, and explain behavior and the cognitive and biological processes that underlie it.
13.8K