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Updated: Mar 23, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
Published on: May 3, 2018
Relation between periodontal disease and arterial stiffness
L N Nicolosi1,2, P G Lewin2, J J Rudzinski2
1Department of Cardiology, Spanish Hospital of Buenos Aires, Buenos Aires, Argentina.
Severe periodontal disease is linked to poorer arterial stiffness and endothelial function (EF). These vascular health markers worsen with increased periodontal disease severity, highlighting a connection between oral health and cardiovascular risk.
Area of Science:
- Cardiovascular Research
- Periodontology
- Vascular Biology
Background:
- Periodontal disease is implicated in atherosclerosis.
- Previous studies explored its link with intimal thickness and endothelial function (EF).
Purpose of the Study:
- To compare arterial stiffness and EF parameters between patients with and without severe periodontal disease (SPD).
Main Methods:
- Carotid Doppler ultrasound assessed arterial stiffness (compliance, elastic modulus (EM), β stiffness index (βSI)) and vascular EF.
- Patients were categorized into groups with and without SPD, excluding those with known cardiovascular pathology.
Main Results:
- Patients with SPD showed significantly worse arterial stiffness (higher EM and βSI) and lower EF compared to controls.
- Clinical attachment level correlated moderately with EM, βSI, and negatively with EF.
Conclusions:
- Arterial stiffness and EF parameters are impaired in patients with severe periodontal disease.
- The severity of periodontal disease correlates with these vascular health indicators.
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