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Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

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Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
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Cancer Prevention02:59

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancer-Critical Genes II: Tumor Suppressor Genes01:05

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Community-Guided Focus Group Analysis to Examine Cancer Disparities.

Jennifer C Schaal, Alexandra F Lightfoot, Kristin Z Black

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    This study highlights how a collaborative approach to analyzing patient experiences can improve cancer care equity. Engaging diverse partners in research enhances transparency and accountability in addressing treatment disparities.

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    Area of Science:

    • Health Disparities Research
    • Community-Based Participatory Research (CBPR)
    • Qualitative Research Methods

    Background:

    • The Accountability for Cancer Care through Undoing Racism™ and Equity (ACCURE) intervention aims to reduce disparities in cancer treatment for Black and White patients.
    • ACCURE employs a CBPR approach, involving academic researchers, community organizations, and cancer center staff.

    Purpose of the Study:

    • To describe the collaborative process of conducting focus groups and analyzing data for the ACCURE intervention.
    • To inform a "power analysis" of the cancer care system and the development of the Healthcare Equity Education and Training (HEET) component.

    Main Methods:

    • Eight focus groups were conducted with Black and White breast and lung cancer survivors at two cancer centers.
    • Participants shared critical incidents ("pressure point encounters") affecting treatment continuation.
    • Community and academic partners collaborated on all research stages, including data collection and analysis.

    Main Results:

    • Collaborative data analysis enriched the research process.
    • The partnership's capacity was strengthened through shared decision-making.
    • Enhanced transparency and accountability were achieved in the research approach.

    Conclusions:

    • A community-medical-academic partnership model can effectively address cancer care disparities.
    • Collaborative qualitative analysis is a valuable tool for systems-change interventions.
    • The ACCURE project's methodology provides a framework for equitable cancer care research.