Related Experiment Video
Updated: Mar 23, 2026

Modeling The Lifecycle Of Ebola Virus Under Biosafety Level 2 Conditions With Virus-like Particles Containing Tetracistronic Minigenomes
Published on: September 27, 2014
Modelling Ebola within a community
R N Leander1, W S Goff1, C W Murphy1
1Department of Mathematical Sciences,Middle Tennessee State University,Murfreesboro,TN,USA.
Abstract:
The 2014 Ebola epidemic was the largest on record. It evidenced the need for improved models of the spread of Ebola. In this research we focus on modelling Ebola within a small village or community. Specifically, we investigate the potential of basic Susceptible-Exposed-Infectious-Recovered (SEIR) models to describe the initial Ebola outbreak, which occurred in Meliandou, Guinea. Data from the World Health Organization is used to compare the accuracy of various models in order to select the most accurate models of transmission and disease-induced responses. Our results suggest that (i) density-dependent transmission and mortality-induced behavioural changes shaped the course of the Ebola epidemic in Meliandou, while (ii) frequency-dependent transmission, disease-induced emigration, and infection-induced behavioural changes are not consistent with the data from this epidemic.
Related Concept Videos
Cross-reactivity
Models of Health Promotion and Illness Prevention I
The health belief model (HBM) attempts to predict health-related behavior in specific belief patterns. According to the HBM, a person's...
Models of Health Promotion and Illness Prevention II
The agent-host-environment model states that disease results...
Steps in Outbreak Investigation
Modeling with Differential Equations
Community Based Intervention
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...

