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Cutaneous perivascular epithelioid cell tumors: A review on an infrequent neoplasm
Mar Llamas-Velasco1, Luis Requena1, Thomas Mentzel1
1Mar Llamas-Velasco, Department of Dermatology, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Abstract:
"Perivascular epithelioid cutaneous" cell tumors (PEComa) are a family of mesenchymal tumors with shared microscopic and immunohistochemical properties: They exhibit both smooth muscle cell and melanocytic differentiation. Non-neoplastic counterpart of PEComa's cells are unknown, as well as the relationship between extracutaneous PEComa and primary cutaneous ones. We will review the clinical setting, histopathologic features, chromosomal abnormalities, differential diagnosis and treatment options for cutaneous PEComa.
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