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Updated: Mar 23, 2026

A Novel Method to Model Chronic Traumatic Encephalopathy in Drosophila
Published on: July 4, 2017
Chronic Traumatic Encephalopathy and Movement Disorders: Update
Apameh Tarazi1,2, Charles H Tator1,3,4, Maria Carmela Tartaglia5,6,7
1Division of Neurology, Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Canada.
Abstract:
Association of repetitive brain trauma with progressive neurological deterioration has been described since the 1920s. Punch drunk syndrome and dementia pugilistica (DP) were introduced first to explain symptoms in boxers, and more recently, chronic traumatic encephalopathy (CTE) has been used to describe a neurodegenerative disease in athletes and military personal with a history of multiple concussions. Although there are many similarities between DP and CTE, a number of key differences are apparent especially when comparing movement impairments. The aim of this review is to compare clinical and pathological aspects of DP and CTE with a focus on disorders of movement.
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