Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

1.0K
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
1.0K
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

1.4K
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
1.4K
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

896
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
896
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

1.0K
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
1.0K
Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

963
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
963
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

1.5K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enriched environment improves sevoflurane-induced cognitive impairment during late-pregnancy via hippocampal histone acetylation.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2020
Same author

A portable point-of-care testing system to diagnose lung cancer through the detection of exosomal miRNA in urine and saliva.

Chemical communications (Cambridge, England)·2020
Same author

Difluoroketenimine: Generation from Difluorocarbene and Isocyanide and Its [3 + 2] Cycloadditions with Alkenes or Alkynes.

The Journal of organic chemistry·2020
Same author

Genome-wide identification and integrated analysis of lncRNAs in rice backcross introgression lines (BC<sub>2</sub>F<sub>12</sub>).

BMC plant biology·2020
Same author

Tetrahydrocurcumin mitigates acute hypobaric hypoxia-induced cerebral oedema and inflammation through the NF-κB/VEGF/MMP-9 pathway.

Phytotherapy research : PTR·2020
Same author

Transcriptional analyses reveal the molecular mechanism governing shade tolerance in the invasive plant <i>Solidago canadensis</i>.

Ecology and evolution·2020

Related Experiment Video

Updated: Mar 23, 2026

Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment
04:05

Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment

Published on: May 31, 2024

973

Post-infectious and non post-infectious irritable bowel syndrome: A comparative study.

Jianbo Wang1, Shihua Lu2, Shijie Zhao3

  • 1Dr. Jianbo Wang, Department of Digestion Internal Medicine, The Affiliated Hospital of Shandong University of, Traditional Chinese medicine, Jinan, Shandong province, China.

Pakistan Journal of Medical Sciences
|March 30, 2016
PubMed
Summary

Post-infectious irritable bowel syndrome (PI-IBS) presents with more diarrhea and anxiety than non-PI-IBS. PI-IBS also shows higher levels of C-reactive protein (CRP) and intestinal fatty acid binding protein (IFABP), suggesting different mechanisms and treatment strategies.

Keywords:
Gastrointestinal symptom rating scale (GSRS)Intestinal fatty acid binding protein (IFABP)None post-infectious irritable bowel syndrome (NPI-IBS)Post-infectious irritable bowel syndrome (PI-IBS)Self-rating anxiety scale (SAS)

More Related Videos

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
09:44

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

23.1K
Investigating Intestinal Inflammation in DSS-induced Model of IBD
08:43

Investigating Intestinal Inflammation in DSS-induced Model of IBD

Published on: February 1, 2012

69.3K

Related Experiment Videos

Last Updated: Mar 23, 2026

Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment
04:05

Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment

Published on: May 31, 2024

973
Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
09:44

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

23.1K
Investigating Intestinal Inflammation in DSS-induced Model of IBD
08:43

Investigating Intestinal Inflammation in DSS-induced Model of IBD

Published on: February 1, 2012

69.3K

Area of Science:

  • Gastroenterology
  • Immunology
  • Microbiology

Background:

  • Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder.
  • Post-infectious IBS (PI-IBS) is a subtype triggered by gastrointestinal infections.
  • Understanding the differences between PI-IBS and non-PI-IBS is crucial for targeted treatment.

Purpose of the Study:

  • To compare the clinical and experimental characteristics of PI-IBS and non-PI-IBS.
  • To identify potential biomarkers differentiating the two IBS subtypes.
  • To inform distinct therapeutic strategies for PI-IBS.

Main Methods:

  • Recruited 89 IBS patients, categorizing them into PI-IBS and non-PI-IBS groups.
  • Collected clinical data, including gastrointestinal symptom rating scale (GSRS) and self-rating anxiety scale (SAS) scores.
  • Measured serum levels of C-reactive protein (CRP) and intestinal fatty acid binding protein (IFABP).

Main Results:

  • PI-IBS patients exhibited a higher prevalence of diarrhea (70.8% vs 19%) and elevated anxiety scores (60.4% vs 34.1%) compared to non-PI-IBS.
  • Significantly higher levels of IFABP and CRP were observed in the PI-IBS group.
  • No significant differences in age, gender, or overall GSRS scores were found between the groups.

Conclusions:

  • PI-IBS appears to have distinct underlying mechanisms compared to non-PI-IBS.
  • Elevated CRP and IFABP levels may serve as indicators for PI-IBS.
  • Tailored treatment approaches are warranted for PI-IBS management.