Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Parathyroid Glands00:59

The Parathyroid Glands

5.7K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
5.7K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

4.2K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
4.2K
Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

7.4K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
7.4K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

6.4K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
6.4K
Synthesis and Functions of Calcitonin00:51

Synthesis and Functions of Calcitonin

5.2K
Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
5.2K
The Thyroid Gland01:23

The Thyroid Gland

8.5K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
8.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of Femtosecond Laser in Situ Keratomileusis on the Choriocapillaris Perfusion and Choroidal Thickness in Myopic Patients.

Current eye research·2020
Same author

Mid-Task Physical Exercise Keeps Your Mind Vigilant: Evidences From Behavioral Performance and EEG Functional Connectivity.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2020
Same author

Impact of vitamin D on human embryo implantation-a prospective cohort study in women undergoing fresh embryo transfer.

Fertility and sterility·2020
Same author

Efficient removal of Hg<sup>2+</sup> from aqueous solution by a novel composite of nano humboldtine decorated almandine (NHDA): Ion exchange, reducing-oxidation and adsorption.

Journal of hazardous materials·2020
Same author

Spatiotemporal transfer of nitric oxide in patient-specific atherosclerotic carotid artery bifurcations with MRI and computational fluid dynamics modeling.

Computers in biology and medicine·2020
Same author

Essentiality of CTNNB1 in Malignant Transformation of Human Embryonic Stem Cells under Long-Term Suboptimal Conditions.

Stem cells international·2020

Related Experiment Video

Updated: Mar 23, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

2.4K

Effects of thyroid cystectomy for primary hyperparathyroidism on immune function.

Xiangdang Yin1, Liang Hu2, Xiaochun Wang3

  • 1Xiangdang Yin, Department of Oral-Maxillofacial-Thyroid Oncosurgery, Jilin Cancer Hospital, Changchun 130001, China.

Pakistan Journal of Medical Sciences
|March 30, 2016
PubMed
Summary

Endoscopic thyroidectomy for primary hyperparathyroidism shows fewer complications and promotes faster recovery of calcium and phosphorus levels compared to open surgery, with minimal impact on immune function.

Keywords:
Endoscopic thyroidectomyImmune functionPrimary hyperparathyroidismThyroid hormone

More Related Videos

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
07:13

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation

Published on: March 14, 2017

15.4K
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

5.2K

Related Experiment Videos

Last Updated: Mar 23, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
03:57

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy

Published on: July 14, 2023

2.4K
Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
07:13

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation

Published on: March 14, 2017

15.4K
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

5.2K

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Immunology

Background:

  • Primary hyperparathyroidism is often caused by parathyroid cysts.
  • Surgical intervention is necessary for managing symptomatic primary hyperparathyroidism.
  • Assessing the impact of surgical techniques on immune function is crucial.

Purpose of the Study:

  • To compare the effects of endoscopic thyroidectomy versus conventional open thyroidectomy on immune function in patients with primary hyperparathyroidism.
  • To evaluate postoperative recovery of thyroid hormone and mineral levels.
  • To assess complication rates associated with each surgical approach.

Main Methods:

  • A randomized controlled trial involving 92 patients with parathyroid cysts and primary hyperparathyroidism.
  • Treatment group: Endoscopic thyroidectomy via anterior chest wall areolar approach.
  • Control group: Conventional open thyroidectomy.

Main Results:

  • Both groups showed similar pre-operative immune function and hormone levels.
  • Post-operatively, both groups had altered thyroid hormones (increased FT3/FT4, decreased TSH).
  • Endoscopic surgery resulted in faster immune recovery (NK%, CD3+%, CD4+%, CD8+%) and better calcium/phosphorus balance, with significantly lower complication rates.

Conclusions:

  • Endoscopic thyroidectomy through the anterior chest wall areolar approach is a viable option for primary hyperparathyroidism.
  • This technique reduces complication incidence and aids in faster mineral level recovery.
  • The procedure appears to have a milder impact on immune and thyroid hormone levels compared to open surgery.