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Multiple sclerosis in Istria, Yugoslavia.

E Materljan, J Sepcić, L Antonelli

    Neurologija
    |January 1, 1989
    PubMed
    Summary
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    This study investigated multiple sclerosis (MS) in Istria, finding a prevalence rate of 25.0/10(5) inhabitants. These findings place Istria in a moderate-to-high risk zone for this neurological disease.

    Area of Science:

    • Neurology
    • Epidemiology

    Background:

    • Multiple sclerosis (MS) is a chronic neurological disease with varying prevalence globally.
    • Understanding regional variations in MS occurrence is crucial for public health planning.

    Purpose of the Study:

    • To determine the prevalence and incidence of multiple sclerosis in Istria, Yugoslavia.
    • To characterize the epidemiological features of MS in the region.

    Main Methods:

    • An epidemiological survey was conducted in Istria during 1980-1981.
    • Health care information sources were reviewed to identify potential MS cases.
    • Schumacher et al. diagnostic criteria were applied to confirm clinically definite MS cases.

    Main Results:

    • A total of 47 clinically definite multiple sclerosis cases were identified.

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  • The prevalence rate of MS on March 31st, 1981, was 25.0 per 10(5) inhabitants (CI: 19.9-38.9).
  • The average age of onset was approximately 30 years, with a female-to-male sex ratio of 2.13. The average duration of illness was 16.5 years, and the annual incidence rate was 1.5 per 10(5) inhabitants.

    • Conclusions:

    • Istria's MS prevalence rate suggests it is a region with moderate-to-high risk for the disease.
    • The epidemiological profile of MS in Istria includes a later age of onset and a higher prevalence in females.
    • Further research is warranted to explore the etiological factors contributing to MS in this region.