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Updated: Mar 23, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
[Diagnostic methods in the clinical evaluation of iridocorneal endothelial syndrome]
Background:
This article presents a patient with iridocorneal endothelial (ICE) syndome.
Case Report:
A 35-year-old man presented with unilateral slightly decreased visual acuity. Examination by slit-lamp biomicroscopy of the affected eye revealed alterations to the corneal endothelial layer, which had a silver-grey and hammered appearance. Corectopia with the pupil drawn towards an area with peripheral anterior synechiae could be gonioscopically detected. In vivo confocal microscopy of the cornea revealed alterations of the corneal endothelial layers of the affected eye, namely epithelization of the endothelium with pleomorphic epithelioid cells of irregular size and shape, indistinct borders and hyperreflective nuclei.
Conclusion:
In vivo confocal microscopy of the cornea is a sensitive diagnostic method for the rapid and early diagnosis of ICE syndrome.
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